Shervyen Newton and Gavin Garay each had two hits, while the pitching staff threw a solid game, allowing nine hits.
With a wild game on Tuesday night ending a little past 10 p.m., both teams had a roughly 13 hours of rest before the 11 a.m. start time on Wednesday.
Much like Tuesday night, both teams got off to good starts in the first two frames.
Kingsport (12-8) got an early edge with two runs in the bottom of the first.
Guillermo Granadillo started things off with stealing home while Luis Santana stole second and then advance to third on the bad throw.
Mark Vientos got Santana home on the next at-bat with a RBI single.
The Reds (6-14) countered in the top half of the second with a Hunter Oliver solo home run to left center field.
The Mets had the early 2-1 lead.
In the bottom of the fourth inning, Mets first baseman Gavin Garay crushed a ball to the deepest part of the park in straightaway center that increased the Kingsport lead to 3-1.
METS EXTEND LEAD
Yoel Romero laid down a bunt single in the sixth inning to score Jarred Kelenic from third. Kelenic reached base via a walk and his path home was aided by a Garay single.
BIG GAME JOSE
Mets starter Jose Butto got his first win of the season in six innings of work and he struck out eight batters. He did not allow a walk and had only one run scored against him.
Dedniel Nunez got his first save of the season as finished off the game in three inning of relief. He struck out one and allowed just one hit.
FOR THE FOES
Oliver was the only Greeneville player to record multiple hits in the game, finishing 3-for-4 with two other singles along with his homer.
The Mets and Reds will continue the season on Thursday with the third game of four beginning at 6:30 p.m.